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Pool Lab Publications:  (underline = Pool lab member; * = equal contributions)

Pool JE, Braun DT, Lack JB (2017) Parallel evolution of cold tolerance within Drosophila melanogaster.
Mol Biol Evol, 34:349-360.  PDF

Hervas S, Sanz E, Casillas S, Pool JE, Barbadilla A (2017) PopFly: the Drosophila population genomics browser. Bioinformatics, Accepted.

Lack JB, Lange JD, Tang AD, Corbett-Detig RB, Pool JE (2016) A thousand fly genomes: an expanded Drosophila Genome Nexus. Mol Biol Evol, 33:3308-3313.  PDF

Pool JE (2016) Genetic mapping by bulk segregant analysis in Drosophila: experimental design and simulation-based inference. Genetics, 204:1295-1306PDF

Bastide H, Lange JD, Lack JB, Yassin A, Pool JE (2016) A variable genetic architecture of melanic evolution in Drosophila melanogaster. Genetics, 204:1295-1306.  PDF

Yassin A*, Delaney EK*, Reddieux A, Bastide H, Appleton N, Seher T, Podlaja O, Lack JB, Barmina O, Allen S, David JR, Chenoweth S, Pool JE, Kopp A (2016) Pdm3 is responsible for recurrent evolution of female-limited color dimorphism in Drosophila. Curr Biol, 26:2412-2422.  PDF

Lack JB, Yassin A, Johanning EJ, Sprengelmeyer QD, David JR, Pool JE (2016) Life history evolution and cellular mechanisms associated with increased size in high altitude Drosophila. Evol Ecol 6:5893-5906.  PDF

Lange JD, Pool JE (2016) A haplotype method detects diverse scenarios of local adaptation from genomic sequence variation. Mol Ecol 25:3081-3100.  PDF

Yassin A, Debat V, Bastide H, Gadesweski N, David JR*, Pool JE* (2016) Recurrent specialization on a toxic fruit in an island Drosophila population. Proc Natl Acad Sci USA 113:4771-4776.  PDF1  PDF2

Lack JB, Monette MJ, Johanning EJ, Sprengelmeyer QD, Pool JE (2016) Decanalization of wing development accompanied the evolution of large wings in high altitude Drosophila. Proc Natl Acad Sci USA 113:1014-1019.  PDF1  PDF2

Yassin A, Bastide H, Chung H, Veuille M, David JR, Pool JE (2016) Ancient balancing selection at tan underlies female color dimorphism in Drosophila erecta. Nat Commun 7:10400.  PDF

Gasch AP, Payseur BA, Pool JE (2016) The power of natural variation for model organism biology. Trends Genet 32:147-154.  PDF1  PDF2

Pool JE (2015) The mosaic ancestry of the Drosophila Genetic Reference Panel and the
D. melanogaster reference genome reveals a network of epistatic fitness interactions. Mol Biol Evol 32:3236-3251.  PDF

Fabian DK, Lack JB, Vinayak M, Schlötterer C, Schmidt PS, Pool JE, Flatt T (2015) Spatially varying selection shapes life history clines among populations of Drosophila melanogaster from sub-Saharan Africa. J Evol Biol 28:826-840.

Lack JB, Cardeno CM, Crepeau MW, Taylor W, Corbett-Detig RB, Stevens KA, Langley CH, Pool JE (2015) The Drosophila Genome Nexus: a population genomic resource of 623 Drosophila melanogaster genomes, including 197 from a single ancestral range population.  Genetics, 199:1229-1241.  PDF

Bastide H*, Yassin A*, Johanning EJ, Pool JE (2014) Pigmentation in Drosophila melanogaster reaches its maximum in Ethiopia and correlates most strongly with ultra-violet radiation in sub-Saharan Africa. BMC Evol Biol 14:179.
  PDF

Pitchers W, Pool JE, Dworkin I (2013) Altitudinal clinal variation in wing size and shape in African Drosophila melanogaster: one cline or many? Evolution 67:438-452.
  PDF

Hua Z, Pool JE, Schmitz RJ, Schultz MD, Shiu S-H, Ecker JR, Vierstra RD (2013) Epigenomic programming contributes to the genomic drift evolution of the F-Box protein superfamily in Arabidopsis. Proc Natl Acad Sci USA 110:16927-16932.

Pool JE
, Corbett-Detig RB, Sugino RP, Stevens KA, Cardeno CM, Crepeau MW, Duchen P,  Emerson JJ, Saelao P, Begun, DJ, Langley CH (2012) Population genomics of sub-Saharan Drosophila melanogaster: African diversity and non-African admixture. PLoS Genetics 8:e1003080.
  PDF  Supplement


Pool Publications:
  (pre-UW)

Langley CH, Stevens KA, Cardeno C, Lee Y-C, Schrider D, Pool JE, Langley S, Suarez C, Corbett-Detig R, Kolaczkowski B, Kern AD, Dewey CN, Song Y, Hahn MW, Begun DJ (2012) Population genomics of Drosophila melanogaster. Genetics 192:533-598.  PDF

Wang L, Luzynski K, Pool JE, Janoušek V, Dufkova P, Mrkvicová Vyskočilová M, Teeter K, Nachman M, Munclinger P, Macholan M, Pialek J, Tucker PK (2011) Measures of linkage disequilibrium among neighboring SNPs indicate asymmetries across the house mouse hybrid zone. Mol Ecol 14:2985-3000.

Yi X*, Liang Y*, Huerta-Sanchez E*, Jin X*, Cuo ZXP*, Pool JE*, et al. (2010) Sequencing of fifty human exomes reveals adaptation to high altitude. Science 329:75-78.
  PDF1  PDF2

Pool JE, Hellmann I, Jensen JD, Nielsen R (2010) Population genetic inference from genomic sequence variation. Genome Res 20:291-300.
  PDF

Rebeiz M, Pool JE, Kaessner V, Aquadro CF, Carroll SB (2009) Stepwise modification of a modular enhancer underlies local adaptation in a Drosophila population. Science 326:1663- 1667.
  PDF1  PDF2

Pool JE, Nielsen R (2009) Inference of historical changes in migration rate from the lengths of migrant tracts. Genetics 181:711-719.
  PDF

Wang J, et al. (2008) The diploid genome sequence of an Asian individual. Nature 456:60-65.

Pool JE, Nielsen R (2008) The impact of founder events on chromosomal variability in multiply mating species. Mol Biol Evol 25:1728-1736.
  PDF

Pool JE, Nielsen R (2007) Population size changes reshape genomic patterns of diversity. Evolution 62:3001-3006.
  PDF1  PDF2

Pool JE, Aquadro CF (2007) The genetic basis of adaptive pigmentation variation in Drosophila melanogaster. Mol Ecol 16:2844-2851. 
PDF1  PDF2

Wong A, Jensen JD, Pool JE, Aquadro CF (2007) Phylogenetic incongruence in the Drosophila melanogaster species group. Mol Phyl Evol 43:1138-1150.

Pool JE, Aquadro CF (2006) History and structure of sub-Saharan populations of Drosophila melanogaster. Genetics 174:915-929.
  PDF

Pool JE, Wong A, Aquadro CF (2006) Finding of male-killing Spiroplasma infecting Drosophila melanogaster in Africa implies transatlantic migration of this endosymbiont. Heredity 97:27-32.
  PDF

Pool JE, Bauer DuMont V, Mueller JL, Aquadro CF (2006) A scan of molecular variation leads to the narrow localization of a selective sweep affecting both Afrotropical and cosmopolitan populations of Drosophila melanogaster. Genetics 172:1093-1105.
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